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The concomitant administration of Viramune with NNRTIs is not recommendedsee section 4.4

Rhabdomyolysis has been observed in patients experiencing skin and/or liver reactions associated with nevirapine use.

The safety and efficacy of Viramune has not been established in patients with significant underlying liver disordersViramune is contraindicated in patients with severe hepatic impairmentChild-Pugh Csee section 4.3Pharmacokinetic results suggest caution should be exercised when nevirapine is administered to patients with moderate hepatic dysfunctionChild-Pugh BPatients with chronic hepatitis B or C and treated with combination antiretroviral therapy are at an increased risk for severe and potentially fatal hepatic adverse reactionsIn the case of concomitant antiviral therapy for hepatitis B or Cplease refer also to the relevant product information for these medicinal products.

The active substance in Viramunenevirapineis a non-nucleoside reverse-transcriptase inhibitorNNRTIIt blocks the activity of reverse transcriptasean enzyme produced by HIV-1 that allows it to infect cells in the body and make more virusesBy blocking this enzymeViramunetaken in combination with other antiviral medicinesreduces the amount of HIV-1 in the blood and keeps it at a low levelViramune does not cure HIV-1 infection or AIDSbut it may delay the damage to the immune system and the development of infections and diseases associated with AIDS.

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take generic viramune nevirapine regularly and make sure you renew your prescription on time.

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